Groundbreaking method to review mechanistic research on lifestyle factors & cancer

We have teamed up with the University of Bristol to increase understanding of the links between diet, weight, physical activity and cancer

21 October 2015

Globally, there is currently no standardised way to review the vast amount of research on the mechanisms by which lifestyle factors can cause cancer. This innovative new work offers a comprehensive and systematic way of collating and reviewing such research, will help identify the gaps in our knowledge about the mechanisms, and inform the direction of future research.

Developed by Dr Sarah Lewis and Professor Richard Martin of the University of Bristol, the groundbreaking new method of assessing mechanistic studies could become the global mainstream approach to assessing such research. The comprehensive method is currently being tested by two teams from Maastricht University and the German Cancer Research Center, and a full validation study is expected to take place next year.

In addition, an online tool has been developed to automate part of the process. This online web-based tool will enable scientists from around the world to identify and visually display the mechanistic studies by specific exposure and outcome.

Our scientific advisor, Professor Martin Wiseman, is scheduled to discuss this project at the Federation of European Nutrition Societies (FENS) conference later today.