Science and football – while they may not seem like they have much in common, the disciplines meet in the person of Dr Frankie Brown. Frankie is an immunologist and former member of Scotland’s women’s team who has represented her country 96 times on the international stage.
Our funding helped Frankie realise her other dream of researching ways exercise can benefit those living with and beyond cancer.
Helping people with blood cancer
Frankie Brown with her Scotland team-mates
Under Dr Campbell from the University of Bath, Frankie worked in a team on a project funded by us investigating the effects of exercise on the health of patients with chronic lymphocytic leukaemia, a form of blood cancer that affects around 4,000 new people every year in the UK.
The team evaluated the safety and feasibility of a progressive exercise programme for these patients – many who were over 60. Essentially, they tested a “recipe for how to run a big study” more effectively, and even adapted it to continue successfully during the COVID pandemic.
She was inspired by her own background as a professional footballer, as well as her personal experience with cancer:
“When I was finishing up my PhD, my mum died of breast cancer. That was a real trigger moment for me to look more into oncology. I just couldn’t get my head around it – she had been so healthy. I would wonder, what’s going on here?
“I already knew a lot about health and monitoring my body for football. I started playing football very young, playing with my little brother, and I haven’t stopped since. I was in the Scotland under 17s, then the under 19s, and got into the full squad when I was 21 and was there for 10 years.
“Having spent my whole life in a high-performance environment, with everything being tested and monitored, I became more aware of how my body reacts to even very small shifts in circumstances and situations. It wasn’t hard for me to see how those tiny changes that are so important to athletes can be important for everybody.”
This inspired Frankie to become a researcher, where she found herself on the team led by Dr Campbell and funded by us. There were, however, some setbacks along the way – the biggest being the COVID-19 pandemic. Thanks to the flexibility of our funding programme, Frankie says she and the rest of the team were able to pivot from designing the programme to be in-person, to buying the participants exercise bikes and running a group session over Zoom.
“We had to shift the whole design of the exercise sessions to be home-based and World Cancer Research Fund allowed us to deliver exercise bikes to the participants’ homes. Without that, the trial would have fallen apart.“
‘The more muscle mass you have as you get older, the more independent you will be’
The data showed a 2% increase in lean mass in the exercise group compared with a 0.4% decrease in the control group. This is a significant benefit, as Frankie explains: “The data we have now and the study we’ve done shows that any gain a patient can make with their performance can make a huge difference to their own wellbeing.
“An increase in lean mass – in other words, in muscle mass – in these patients is a huge thing, especially in people over 60. The more muscle mass you have as you get older the more independent you will be. One of our participants lived up some stairs, and whenever I think about the study, I think about them and hope that my work has made it easier for them to get the shopping up and down to their home.”
These results have informed the design of a larger study where Frankie and her team will assess the tumour-suppressing effects and mechanisms of exercise in humans.
Frankie is very vocal about the impact of our support on her work: “In my experience, World Cancer Research Fund has been incredibly supportive of me as a young academic. They’ve provided amazing flexibility at a very uncertain time. I wouldn’t have been able to achieve any of this without you.”
What do people who took part in the study say?
I was really unfit when I started the trial and in the battle with the bike I came near to collapse! But the research team were watching and got me sorted me out. So I didn't collapse and in fact went on to add 2kg to my muscle mass.
What do people who took part in the study say?
I’m pleased that I took part in the study as although I already did some exercise it pushed me out of my comfort zone and has left me feeling more positive about the future giving me a way to ‘fight back’.
Governments, researchers and organisations (including World Cancer Research Fund) need to keep track of how the number of cancer cases in the UK changes from year to year. This helps with the planning, development, and undertaking of cancer research and evidence-based policy.
Each of the 4 devolved nations of the UK (England, Northern Ireland, Scotland and Wales) regularly report cancer incidence, as well as mortality, through their Cancer Registries. World Cancer Research Fund then uses these data to produce detailed cancer incidence and mortality tables and publishes this information on our website. At the same time, we analyse the data to see how cancer numbers are changing.
Comparing cases of cancer in the UK from 2019 to 2021
In 2021, the most recent year for which data are available, there were 395,181 cases of cancer in the UK. Of these, 200,870 were in men (up very slightly from 200,386 in 2019) and 194,311 in women (up from 187,434 in 2019).
Cancer cases: 2019 and 2021
| Men | Women | Total | |
|---|---|---|---|
| 2019 | 200,386 | 187,434 | 387,820 |
| 2021 | 200,870 | 194,311 | 395,181 |
In terms of percentage changes, cancer incidence among women increased by 3.7% between 2019 and 2021 but stayed pretty much the same for men (increasing by only 0.2%). This means that while the number of cases only increased significantly among women, there was still an overall increase of approximately 7,400 cases, or 2%.
So, although men still experience more cases of cancer than women, the difference in the number of cases between the sexes fell from approximately 12,900 in 2019 to approximately 6,500 in 2021.
How are cases of the most common cancers changing in men and women?
Breast cancer remained the most common type of cancer among women in the UK, with 59,155 new cases in 2021 – approximately 30% of all cancers. This was followed by lung (23,972) and colorectal cancer (21,945). Our analysis shows that, between 2019 and 2021, cases of all 3 increased in women.
Among men, prostate cancer was the most common cancer in the UK. In 2021, 51,575 cases of prostate cancer were diagnosed – approximately 26% of all new cases of cancer – followed by colorectal (27,969) and lung (24,932). While cases of prostate and lung cancer decreased, colorectal cancer cases increased.
Cases of the top 3 site-specific cancers in the UK in 2019 and 2021
| 2019 | 2021 | |
|---|---|---|
| Women | ||
| Breast | 56,601 | 59,115 |
| Lung | 23,614 | 23,972 |
| Colorectal | 20,759 | 21,945 |
| Men | ||
| Prostate | 55,068 | 51,575 |
| Colorectal | 25,303 | 27,969 |
| Lung | 25,140 | 24,932 |
Why is the overall number of cancer cases increasing in women but not in men?
There could be several reasons for this. One of the most important is that approximately 40% of all cancers could be prevented by changes in modifiable risk factors – things in our behaviour or environment that can be changed and make the development of cancer more or less likely. For 2021, this would equate to approximately 158,000 cases of cancer prevented.
When we talk about modifiable risk factors for cancer, these include not smoking, avoiding the sun, maintaining a healthy body weight, being physically active, and eating a healthy diet.
> More information about what is included in a healthy diet
Simply put, it is likely that any changes in the number of new cancer cases are partially explained by changes in the rates of these behaviours. This will be particularly true for those cancers for which there is strong evidence that behaviour increases risk. One recent example of this is rates of smoking declining among men while still increasing among women. As a result, it is predicted that cases of lung cancer among women will outnumber those among men in the next couple of years.
The links between modifiable behaviours and cancer are supported by a growing body of research demonstrating that following our Cancer Prevention Recommendations can help people reduce their cancer risk.
More news and blogs on cancer stats
- New guidance developed with experts including patients and service users
- Our Cancer Prevention Recommendations are beneficial after a cancer diagnosis
- Comprehensive review of evidence and recommendations for future research directions
Two new in-depth scientific reports, launched at the World Cancer Congress in Geneva, bring together a full synthesis of the current evidence on diet, nutrition, physical activity and body weight from World Cancer Research Fund International’s Global Cancer Update Programme (CUP Global) on people living with and beyond breast and colorectal cancers.
For the first time, they present guidance for people living with and beyond breast and colorectal cancers, caregivers and health professionals. The reports also discuss the limitations of the existing research and make recommendations for future research to strengthen the evidence base.
Relevant and accessible
The CUP Global research team at Imperial College London conducted 7 systematic reviews, together assessing many thousands of recent research papers, studies and databases. World Cancer Research Fund convened expert panels, including oncologists and researchers, as well as patients and people with lived experience of cancer, to ensure the guidance is relevant and accessible.
Prof Andrew Renehan, Deputy Chair of the CUP Global Expert Committee on Cancer Survivorship, said:
These reports are the culmination of over 2 years of detailed work by World Cancer Research Fund International and the CUP Global partnership. They are a substantial and significant body of work and represent the best synthesis of our knowledge to date. As well as providing guidance for oncology health professionals and people living with and beyond cancer, they offer a clear direction for researchers seeking to advance the field.
Lynette Hill, Public Representative on the CUP Global panel, said:
Our challenge was to translate the complex findings from so many scientific papers into simple messages for people living with and beyond cancer. This will help health professionals to answer questions and inform their patients about the role of diet, physical activity and body weight, and the importance of these to their future health.
The reports show how nutrition, physical activity and body weight affect survival and recurrence. For people living with and beyond breast cancer, there is strong evidence that a physically active lifestyle improves health-related quality of life and that a diet high in fibre may improve health outcomes. For colorectal cancer, the evidence suggests that physically active lifestyles and a diet rich in wholegrain foods, and avoiding sugary drinks, may improve health outcomes and overall survival.
Key evidence in the reports was recently published in a series of linked papers in the International Journal of Cancer, published by the Union for International Cancer Control (UICC),
Dr Sonali Johnson, Head of Knowledge, Advocacy and Policy at the UICC said:
The guidance provided in these reports is about giving people living with cancer the tools they need to take control of their health. By focusing on practical changes such improving diet, staying active and managing weight, we can help reduce the risk of cancer coming back and improve the quality of life for so many, bringing us closer to a world where fewer lives are lost to cancer, and more people can live healthier, longer lives after diagnosis.
World Cancer Research Fund’s CUP Global is the world’s largest source of scientific research on cancer prevention and survivorship through diet, nutrition, physical activity and body weight. It is funded in partnership with American Institute for Cancer Research, World Cancer Research Fund in the UK and Wereld Kanker Onderzoek Fonds in the Netherlands.
Dr Helen Croker, World Cancer Research Fund International’s Assistant Director of Research and Policy, and Head of the CUP Global Secretariat, said:
As an evidence-based organisation, we have used the best available evidence to develop this process and produce practical guidance on diet, physical activity and body weight for people living with and beyond cancer. We hope this guidance will help support people to live longer, healthier lives.
By highlighting gaps in the evidence base, the reports show where further, high-quality research is needed. These include well-designed clinical trials and prospective cohort studies, as well as understanding the biological mechanisms involved. We hope this will be a springboard for further progress.
Download the reports
> Breast cancer
> Colorectal cancer
Download the executive summaries
> Breast cancer
> Colorectal cancer
Summary guidance in the reports
- Suggests that people living with and beyond breast and colorectal cancers consider increasing their physical activity, under the supervision of health care professionals.
- Suggests that people living with and beyond breast and colorectal cancers consider following as many of WCRF/AICR’s Cancer Prevention Recommendations as they are able.
- People diagnosed with breast cancer should consider:
- increasing their dietary fibre intake.
- avoiding gaining weight during and after treatment (if not underweight).
- People diagnosed with colorectal cancer should consider increasing their dietary intake of wholegrain foods, and reducing their sugary drink intake.
Much of the research in these reports build on the 2014 (updated 2018) report: Diet, nutrition, physical activity and breast cancer survivors, which was published as part of the WCRF/AICR Third Expert Report on the links between lifestyle/modifiable behaviours and cancer. At that time, research on cancer survival was limited, but there was enough evidence to conclude that people living with and beyond cancer should follow our Cancer Prevention Recommendations if they can.
Related content
Our helpline is run by a team of oncology specialist dietitians. The service aims to help people get the nutritional advice needed to support their cancer treatment and recovery, and will address issues such as taste changes, appetite loss, nausea and constipation as well as how to maintain a healthy weight during treatment.
It can be hard to get access to the appropriate support around nutrition. If you or your patient or client have ever had a cancer diagnosis, and are looking for evidence-based nutrition, the service is available on Tuesdays (12-2pm) and Thursdays (6-8pm). These hours of operation will be expanded as the year progresses.
Comments on the launch of the new helpline
Christopher Allen, Cancer Support Programme Manager at World Cancer Research Fund comments:
We wanted to provide people with cancer a helpline where they can access expert nutritional information. This can often be difficult through the NHS. Treatments such as chemotherapy can make it more of a challenge to eat as you normally would while absorbing the necessary nutrients – and we’ll offer tips and support to make mealtimes easier and more enjoyable for those with a cancer diagnosis.
Jodie Burdett, who had a breast cancer diagnosis, says:
When I was diagnosed, I looked at which habits I could change. It was difficult to know who to trust as there’s quite a lot of ‘advice’ out there with conflicting and confusing messages. So many of us going through chemotherapy unhelpfully get told, ‘you just need to keep your weight up, eat four cream cakes.
That’s when I came across World Cancer Research Fund; its helpline will play a vital role for so many people going through cancer like me who need information about nutrition.
Debbie Hack, Oncology Specialist Dietitian, who takes calls on the helpline, says:
When I heard about World Cancer Research Fund’s new nutrition helpline my immediate thoughts were ‘at last, something that fills the gap.
Dietetic services for cancer vary significantly across the UK and those affected don’t always have access to credible nutritional support. Our helpline addresses this fundamental need. Some people just require reassurance or guidance on how to access the right information, and now we are here to help with that.
Latest news and blogs
A bowel cancer diagnosis during lockdown shocked our supporter Claire Burlison to the core. But following surgery, she’s now living beyond cancer and trying to follow our Recommendations.
A cancer diagnosis can be devastating for anyone. But when you’re young, energetic – and the world is in the grip of a global pandemic – it’s even harder.
“I was diagnosed with bowel cancer in 2020,” says Claire, “which came as a shock as I’m only in my 40s. Before that, I assumed my irritable bowel syndrome was just getting worse. It was only when I got sharp stomach pains and ended up in A&E that I found out I needed surgery.
“I was expecting bad news, but it still knocked me for six when they phoned and told me I had bowel cancer,” she adds.
Although bowel cancer – like most cancers – is more prevalent in older adults, it’s sadly increasingly common in younger people. Researchers are trying to find out why. Fortunately for Claire, doctors found that the cancer hadn’t spread. Now, having been cancer-free for over 2 years, she’s trying to follow our Recommendations in her daily life to reduce the risk of cancer returning.
Conscious eating
Claire limits alcohol and is much more aware of what she eats – checking food labels to see what’s really in the food she’s buying, and dramatically reducing how much red and processed meat she eats, because of the strong links to bowel cancer.
Exercise is also important for people living beyond cancer – with both physical and mental benefits. For Claire, staying active comes naturally as she is the founder of the international dance phenomenon Clubbercise. Blending simple but effective dance, toning and combat moves, Clubbercise is a workout with a difference aimed at all abilities. The atmosphere is more nightclub than gym, as people dance together in a darkened room with low lighting and flashing LED glow sticks.
Know the symptoms of bowel cancer
Claire says she’s “proud to still be here supporting Bowel Cancer Awareness Month”, which takes place in April every year.
“Thankfully, my cancer was caught early and I’m fine now but many people aren’t so lucky. I’ve lost friends to this terrible disease and I’m keen to raise awareness to help others. If you notice any changes to your bowel habits that last more than a couple of weeks please see your doctor straight away – it could save your life!”
Get the lowdown on bowel cancer
What does our research say about how you can prevent the disease?
