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What role does thyroid hormone metabolism play in liver cancer development?
We aim to assess relationships between blood thyroid hormone levels and risk of hepatocellular carcinoma, and explore underlying mechanistic pathways
How exercise affects cancer survivors with chemotherapy-induced peripheral neuropathy
This research will help us understand the impacts of chemotherapy side-effects on long-term quality of life
Folate status, HPV persistence and cervical cancer risk
A higher concentration of folate in cervical cells, and a chemical change in the DAPK gene, are predictors of HPV persistence
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Early life infections: pathways to prevent adult cancers?
This INSPIRE project investigated whether severe acute infections early in life are linked to risk of cancer in early adulthood.
Studying Burkitt lymphoma among children in sub-Saharan Africa
We want to find out if exposure to mycotoxins (toxic compounds produced by fungi) and infection with Epstein-Barr virus put children at risk of Burkitt lymphoma
Body mass index in childhood and risk of pre-menopausal breast cancer
The study aims to determine whether a larger body size in childhood protects against a risk of pre-menopausal breast cancer.
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The role of diet in the timing of puberty
This project identified modifiable growth and dietary factors that may affect a child’s risk of beginning puberty early
How lifestyle factors in childhood affect adult cancers in low- and middle-income countries (SUNRISE)
The aim of the SUNRISE Pilot Study in Fiji, Botswana, and Kenya is to determine the feasibility and acceptability of the proposed methods for the SUNRISE Study in each country.
How do persistent organic pollutants (POPs) in diet affect endometrial and breast cancer risk?
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Impact of obesity on cancer survival using the Systemic Anti-Cancer Therapy Dataset
Researchers are using an NHS database that captures data for all patients in England that have received cancer treatment in the past decade to better understand survival
What role do proteins in the blood play in the link between metabolic dysfunction and cancer?
Using data on levels of proteins in the blood from large population studies, we aim to understand how metabolic dysfunction leads to the development of cancers
Does liver cancer have an Achilles heel?
Funded by WCRF International, we’re exploring the progression from chronic liver damage caused by diet to the development of cancer
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The ECHO trial: exercise during chemotherapy for ovarian cancer
A study of ovarian cancer in Australia, and whether exercise during chemotherapy is effective
Do environmental pollutants contribute to colorectal cancer?
We hypothesise that exposure to microplastics/nanoplastics and PM2.5 contributes to the onset or speed of colorectal cancer progression, through inflammation and affecting how the immune system works
Lifetime overweight and obesity: impact on cancer survival
This study investigated the exact relationship between obesity and cancer survival
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Uncovering the aetiology of cancers of unknown primary site
Are body composition, activity, diet and alcohol associated with risk of metastatic cancers without an identifiable primary origin?
Rebuilding bone with exercise in multiple myeloma
This study’s objectives are to determine the effect of highly targeted exercise on the bone health and quality of life of people with multiple myeloma.
Exploring selenium and lung cancer risk
We’re studying how selenium may influence lung cancer biology and survival of cancer cells, with the aim of informing future guidance
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Does liver cancer have an Achilles heel?
Funded by WCRF International, we’re exploring the progression from chronic liver damage caused by diet to the development of cancer
Adherence to Mediterranean diet and risk of esophageal, gastric, pancreas, lung and breast cancer
Piet van den Brandt’s research concluded that eating a Mediterranean diet may reduce the risk of lung, postmenopausal breast, oesophagus (squamous cell carcinoma in men), and stomach cancers
Are metabolites associated with obesity causing colorectal cancer?
This research looks at whether the impact of obesity on colorectal cancer is mediated through changes to the circulating metabolome
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Chronic platelet activation – a major link between diet, lifestyle and cancer risk?
We’re funding the first comprehensive prospective study on chronic platelet activation in healthy subjects and subsequent cancer risk
Lifetime overweight and obesity: impact on cancer survival
This study investigated the exact relationship between obesity and cancer survival
Why does food increase or decrease the risk of colorectal cancer?
This research will aim to identify mechanistic (biological) pathways linking diet to colorectal (bowel) cancer
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Physical activity, sedentary behaviour and cancer risk in people with comorbidities
We’re funding a new research project into whether physical activity and sedentary behaviours can affect the risk of developing cancer in people with comorbidities
Non-metastatic colorectal cancer: the role of liver fat, treatment tolerance & prognosis
The aim of this project is to unravel the role of liver fat in relation to acute and long-term clinical outcomes in individuals with large bowel cancer
Does bariatric surgery increase the risk of colorectal cancer?
Bowel cancer risk is increased in individuals with a hospital episode coded as obesity, research shows
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Exploring selenium and lung cancer risk
We’re studying how selenium may influence lung cancer biology and survival of cancer cells, with the aim of informing future guidance
Can chitin, found in insect shells, help prevent colorectal cancer?
We’re investigating whether chitin, a dietary fibre found in insect shells, can prevent colorectal cancer by changing the gut microbiota, reducing gut inflammation and improving DNA modifications in the colon
Non-metastatic colorectal cancer: the role of liver fat, treatment tolerance & prognosis
The aim of this project is to unravel the role of liver fat in relation to acute and long-term clinical outcomes in individuals with large bowel cancer
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Identifying the influence of the microbiome and metabolome on intestinal stem cells
We aim to find out if bacteria affect the behaviour of normal and cancerous intestinal stem cells.
Is exercise safe for people undergoing immunotherapy following a skin cancer diagnosis?
We’ll work with people in Australia who have melanoma to see if an exercise programme is practical, participants attend sessions, follow the plan, and see how they feel about the experience
The feasibility of a diet and physical activity intervention to prevent recurrence in colorectal cancer survivors
Judy Ho identified only a limited service in Hong Kong that offers specific dietary and activity advice to prevent cancer relapse
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Role of body composition and inflammation in multiple myeloma
Investigating how obesity and inflammatory proteins contribute to the development of multiple myeloma, with a focus on whether the amount of fat or where it is stored is more important
The role of maternal folate in childhood leukaemia development
The aim of the project is to address a knowledge gap in understanding how maternal folate levels may influence triggers and chemical marks needed for childhood leukaemia development.
Physical activity and cancer-related fatigue
This research looks at preventing and minimising cancer-related fatigue, improving quality of life and disease outcome