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Early life infections: pathways to prevent adult cancers?
This INSPIRE project investigated whether severe acute infections early in life are linked to risk of cancer in early adulthood.
Physical activity, sedentary behaviour and cancer risk in people with comorbidities
We’re funding a new research project into whether physical activity and sedentary behaviours can affect the risk of developing cancer in people with comorbidities
Harnessing γδ T-cell therapies with exercise to treat multiple myeloma
This study investigates how exercise boosts γδ T-cells to strengthen immune responses against multiple myeloma, with the potential to develop new treatments that improve patient outcomes
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Vitamin D and bladder cancer risk, recurrence and progression
Increased risk of bladder cancer was observed among subjects presenting the lowest concentrations of 25(OH)D. Funded by WCRF International
Impact of obesity on cancer survival using the Systemic Anti-Cancer Therapy Dataset
Researchers are using an NHS database that captures data for all patients in England that have received cancer treatment in the past decade to better understand survival
Rebuilding bone with exercise in multiple myeloma
This study’s objectives are to determine the effect of highly targeted exercise on the bone health and quality of life of people with multiple myeloma.
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Plasma carotenoids, vitamin C and risk of breast cancer
This research found that women with higher levels of certain antioxidants appeared to have lower breast cancer risk
Metabolic signatures of dietary exposures and their association with gastrointestinal cancers
This project will identify metabolic signatures for seven specific dietary exposures whose association with cancer risk has not been convincingly established yet or for which insight into the underlying mechanisms is needed
Body composition and colorectal cancer recurrence and survival
This WCRF-funded research showed that body composition is associated with chances of survival after colorectal cancer and with fatigue
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How many cancers are actually linked to obesity and physical activity?
At least 13 cancers are linked to overweight and obesity, and 3 linked to not being physically active. Are there more cancers that are caused by excess weight and low levels of physical activity?
The effect of physical activity on heart health in blood cancer patients
We’re investigating if you can prevent the adverse cardiometabolic consequences of allogeneic stem cell transplant with physical activity
How does coffee influence large bowel cancer survival?
We’re funding a new research project into how regularly drinking coffee may affect survival from large bowel cancer
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How does physical activity reduce the risk of breast cancer?
Funded by WKOF, we’re working on the key biological pathways linking physical activity with breast cancer risk
Childhood growth and body size across the life course: pathways to breast cancer
This research looks at how a woman’s body size throughout her life affects the risk of breast cancer
Folate status, HPV persistence and cervical cancer risk
A higher concentration of folate in cervical cells, and a chemical change in the DAPK gene, are predictors of HPV persistence
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Isoflavones and lignans in breast cancer among Chinese women
This Hong Kong study will add to the data on the effects of dietary phytoestrogen on breast cancer outcomes
Body composition and chemotherapy toxicity in women with early breast cancer
Can the amount of muscle and fat in the body, and how well the cells of the body are working, predict how people respond to chemotherapy?
How does physical activity lower the risk of cancer?
This research, funded by WCRF International, looks at how our genetics affect immunity, hormones and metabolism, and how these affect activity
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Unravelling the balance between dietary protein and fibre intake for people with bowel cancer
We’re trying to work out the optimal intake of dietary protein for people with bowel cancer, especially when fibre intake is low
How cholesterol metabolism disruptions influence breast cancer development
This study examines the link between cholesterol metabolites, lifestyle factors and breast cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
How western diets alter stem cells and induce colon cancer
This project will investigate which western-style diet-related factors influence the inflammation of stem cells and the development of colon cancer
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How high-intensity exercise and fibre affect immunotherapy outcomes for patients with melanoma
This trial will explore the effects of a high-fibre diet and high-intensity exercise on the gut microbiome, immune function and immunotherapy outcomes in melanoma patients
Colorectal cancer survival in Palestine: a feasibility study on lifestyle factors
This small study will determine if we can undertake a large long-term follow-up study to explore the relationship between lifestyle and survival among large bowel cancer patients.
Biomarkers of acrylamide exposure and risk of endometrial and ovarian cancers
Eric Duell’s research did not support the hypothesis that acrylamide exposure is associated with higher risks for endometrial and ovarian cancers
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Body composition and risk of obesity-related cancers
A better understanding of how body composition affects cancer risk is needed to optimise the recommendations to the general public on body size and cancer
Exercise and outcomes in advanced oesophageal cancer
Will a pre-therapy exercise intervention improve the outcomes of patients with advanced oesophageal cancer?
The ECHO trial: exercise during chemotherapy for ovarian cancer
A study of ovarian cancer in Australia, and whether exercise during chemotherapy is effective
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The effect of food and drink on oesophageal cancer risk in east Africa
This research – funded by WKOF – is looking at whether strong alcohol, heat damage from hot food and drinks, and a restricted diet increase oesophageal cancer risk
Mechanisms of how body fatness affects breast cancer risk
This study, funded by WCRF International, looks at the effect of body fatness on risk of postmenopausal breast cancer
Exploring the mechanisms linking sleep patterns and breast cancer risk
This INSPIRE project shed light on how being a morning person may help reduce breast cancer risk, identifying 2 proteins that could play a key role.
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Non-metastatic colorectal cancer: the role of liver fat, treatment tolerance & prognosis
The aim of this project is to unravel the role of liver fat in relation to acute and long-term clinical outcomes in individuals with large bowel cancer
Biomarkers of acrylamide exposure and risk of endometrial and ovarian cancers
Eric Duell’s research did not support the hypothesis that acrylamide exposure is associated with higher risks for endometrial and ovarian cancers
How does exercise improve cancer-related fatigue in patients with advanced breast cancer?
This study investigates how tailored exercise reduces fatigue and improves quality of life in patients with advanced breast cancer.
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Height and cancer risk: energy restriction and genetic variation
This WKOF-funded research aims to shed light on the mechanisms behind adult-attained height and cancer risk
Uncovering the aetiology of cancers of unknown primary site
Are body composition, activity, diet and alcohol associated with risk of metastatic cancers without an identifiable primary origin?
Identifying which nutrients may cause or protect against prostate cancer
Our research hypothesises that folate, vitamin B12, & iron may increase cancer risk; selenium, vitamin D, E & lycopene may protect against