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Folate status, HPV persistence and cervical cancer risk
A higher concentration of folate in cervical cells, and a chemical change in the DAPK gene, are predictors of HPV persistence
The Butyrate paradox, MicroRNAs and colorectal cancer
A study of microRNAs in dietary reduction of cancer risk in Familial Adenomatous Polyposis patients, funded by WCRF International
Life-S-Can: clinical tool to screen and improve cancer survivorship care and quality of life
This INSPIRE project will create a tool to evaluate body composition, physical activity, diet, alcohol, smoking, sleep and psychosocial distress in cancer survivors
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Weight management in obese cancer patients during curative active treatment
The CANOBESE study evaluates a weight management and exercise program for cancer patients with obesity to improve treatment tolerance and reduce future health risks
Is exercise helpful after oesophageal cancer surgery?
We’re investigating the effect of exercise on quality of life in patients after surgery for oesophageal cancer
Feasibility study for helping patients with chemo-induced peripheral neuropathy
Feasibility study on balance and cognitive training for patients with chemo-induced peripheral neuropathy
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Do different ingredients or cooking methods generate DNA building blocks that promote bowel cancer?
Different ingredients, and cooking and preservation methods, may generate DNA building blocks called non-canonical nucleotides, which could enter cells and cause mutations
What role do proteins in the blood play in the link between metabolic dysfunction and cancer?
Using data on levels of proteins in the blood from large population studies, we aim to understand how metabolic dysfunction leads to the development of cancers
The impact of obesity and insulin on cancer risk
Our research will assess the role of obesity and insulin across multiple cancers using Mendelian randomisation
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Does fructose promote pancreatic cancer through its conversion to acetate?
Pancreatic cancer is among the deadliest forms of cancer and essentially untreatable. How could dietary fructose be promoting its development?
Does exercise during treatment help patients survive cancer?
Studying the molecular mechanisms underlying the protective effect of preoperative exercise in patients with gastro-oesophageal cancer
Studying Burkitt lymphoma among children in sub-Saharan Africa
We want to find out if exposure to mycotoxins (toxic compounds produced by fungi) and infection with Epstein-Barr virus put children at risk of Burkitt lymphoma
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Role of body composition and inflammation in multiple myeloma
Investigating how obesity and inflammatory proteins contribute to the development of multiple myeloma, with a focus on whether the amount of fat or where it is stored is more important
Using personalised diet and physical activity intervention to help stomach cancer patients after a gastrectomy in India
The project aims to determine whether using information about body composition can help personalise a diet and physical activity lifestyle intervention (IBC) and is acceptable to stomach cancer survivors who recently completed treatment
Do sugary drinks increase pancreatic cancer risk?
We’re funding a new research project to identify the processes linking fructose consumption and pancreatic cancer
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Unravelling the balance between dietary protein and fibre intake for people with bowel cancer
We’re trying to work out the optimal intake of dietary protein for people with bowel cancer, especially when fibre intake is low
Vegetables, processed meat, or water: does it matter where we get our nitrate and nitrite from?
Nitrate-rich vegetables are beneficial for health, but evidence links nitrate in water and meat to cancer
Does a poor diet cause health problems for colorectal cancer survivors?
This research aimed to discover if diet affects the health of colorectal cancer survivors, such as depression, fatigue and anxiety
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Childhood growth and body size across the life course: pathways to breast cancer
This research looks at how a woman’s body size throughout her life affects the risk of breast cancer
Using mindfulness to reduce stress in breast cancer patients receiving chemotherapy
This study assesses the effect of a 6-week online mindfulness program on stress reduction and related symptoms in women undergoing chemotherapy for breast cancer
Wearable technology and breast cancer survivors
This study, funded by WCRF International, suggests wearable fitness trackers may improve the quality of life of breast cancer survivors
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Bridging the gap in physical activity and diet support for breast cancer survivors
The aim of this project is to expand our previous study and improve breast cancer survivors’ exercise, healthy diet habits, quality of life and reduce risk of cancer returning
What role do proteins in the blood play in the link between metabolic dysfunction and cancer?
Using data on levels of proteins in the blood from large population studies, we aim to understand how metabolic dysfunction leads to the development of cancers
How many cancers are actually linked to obesity and physical activity?
At least 13 cancers are linked to overweight and obesity, and 3 linked to not being physically active. Are there more cancers that are caused by excess weight and low levels of physical activity?
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Mapping the impact of obesity on the normal breast
This study examines how postmenopausal obesity affects breast cancer risk by analyzing breast tissue changes and testing anti-obesity drugs
How cholesterol metabolism disruptions influence breast cancer development
This study examines the link between cholesterol metabolites, lifestyle factors and breast cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
Metabolic syndrome, gut microbiome, and breast cancer risk in Sub-Saharan African women
The ABCS study examines how metabolic syndrome and the gut microbiome may impact breast cancer risk in Ghanaian women to support prevention strategies and personalised care in Sub-Saharan Africa
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Using mindfulness to reduce stress in breast cancer patients receiving chemotherapy
This study assesses the effect of a 6-week online mindfulness program on stress reduction and related symptoms in women undergoing chemotherapy for breast cancer
Do environmental pollutants contribute to colorectal cancer?
We hypothesise that exposure to microplastics/nanoplastics and PM2.5 contributes to the onset or speed of colorectal cancer progression, through inflammation and affecting how the immune system works
Impact of nutrition and exercise programme after cancer diagnosis
Our goal is to investigate the effectiveness of a comprehensive programme for people after cancer, which includes nutrition, exercise, sleep and stress management, and explores the use of technology such as smart watches
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Using AI chatbots to support families of children with cancer
This INSPIRE project developed an artificial intelligence chatbot called DAPHNE, to address social needs in real-time for families of children with cancer.
Early life infections: pathways to prevent adult cancers?
This INSPIRE project investigated whether severe acute infections early in life are linked to risk of cancer in early adulthood.
Impact of sleep on the development of reproductive system cancers
This INSPIRE project will use data from the UK Biobank and genome-wide association studies to examine the relationship between sleep habits, sleep medications, and the risk of prostate and endometrial cancers
More breast cancer-related research grants
Mapping the impact of obesity on the normal breast
This study examines how postmenopausal obesity affects breast cancer risk by analyzing breast tissue changes and testing anti-obesity drugs
How cholesterol metabolism disruptions influence breast cancer development
This study examines the link between cholesterol metabolites, lifestyle factors and breast cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
Metabolic syndrome, gut microbiome, and breast cancer risk in Sub-Saharan African women
The ABCS study examines how metabolic syndrome and the gut microbiome may impact breast cancer risk in Ghanaian women to support prevention strategies and personalised care in Sub-Saharan Africa